Which choices have the biggest impact? How we eat, how we live, how lucky are we with our genes? What about the therapies out there, stem cells, reprogramming, which one will get us to life extension?
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It all starts by how we set our day in motion. So what is the ideal morning routine and why does everyone have a different opinion on this? Let us explain it simply for you.
For decades, it was thought that with the right lifestyle, people could overcome almost any genetic hurdle. Recent re-evaluations suggest our genetic blueprint has a much stronger influence on our lifespan than previously thought. However, lifestyle still plays a huge role and you should aim to have the best lifestyle as possible.
There is no single "perfect" workout routine, but some principles are universally beneficial to maintain strength and independence as you age.
We naturally lose muscle mass as we age. Strength training is the single most effective way to combat this. Muscle is metabolically active tissue—building it helps regulate blood sugar, boosts metabolism, and keeps your body robust.
A large number of health issues in old age stem from falls. Strong legs and good balance are your primary defense. Exercising your legs is one of the most powerful investments for your future.
A healthy heart and efficient circulatory system are fundamental. Consistent, moderate-intensity exercise (like brisk walking, cycling, or swimming) is incredibly effective.
The true strength doesn't come from the gym but from recovery. High-quality sleep is crucial for longevity. While you sleep, your body is hard at work.
Should you go vegan, or avoid carbs? Is omega-3 a miracle supplement? With so much conflicting nutritional advice, it's crucial to rely on a source based on scientific evidence, not commercial interests.
We recommend NutritionFacts.org, the non-profit project from Dr. Michael Greger. It provides data-driven answers to your questions, empowering you to build a diet that is both healthy and right for you.
Imagine being able to turn back the clock on a cellular level. That's the core idea behind partial reprogramming. Scientists use special proteins (called "Yamanaka factors") to instruct older cells to revert to a more youthful state.
The process "wipes clean" many of the age-related markers and damage from a cell's memory, restoring more youthful function. The key is "partial"—it rejuvenates the cell without completely erasing its identity (like turning a skin cell back into a generic stem cell).
The goal is to rejuvenate tissues and organs from within.
Stem cells are the body's raw materials—they can develop into many different cell types. As we age, our supply of healthy, effective stem cells dwindles, impairing our ability to heal and regenerate tissue.
Stem cell therapies aim to introduce a new supply of healthy stem cells into the body. These new cells can then travel to areas of damage or inflammation, where they help repair tissues, regulate the immune system, and promote a healthier internal environment. It's like bringing in a fresh construction crew to fix an aging building.
As we age, some of our cells become "senescent." Think of them as zombie cells—they stop dividing and refuse to die, but they hang around secreting inflammatory signals that damage nearby healthy cells and contribute to age-related diseases.
Senolytics are a class of drugs designed to selectively target and eliminate these zombie cells. By clearing them out, senolytics can lower inflammation and potentially slow, prevent, or even reverse aspects of age-related decline. It's a therapeutic approach focused on cleaning out the "bad apples" to protect the rest of the barrel.